Home Email this page Print this page Bookmark this page Decrease font size Default font size Increase font size
Noise & Health  
 CURRENT ISSUE    PAST ISSUES    AHEAD OF PRINT    SEARCH   GET E-ALERTS    
 
 Next article
 Previous article
Table of Contents

Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
Citation Manager
Access Statistics
Reader Comments
Email Alert *
Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed3332    
    Printed79    
    Emailed2    
    PDF Downloaded17    
    Comments [Add]    

Recommend this journal

 

 ARTICLE
Year : 2015  |  Volume : 17  |  Issue : 75  |  Page : 83--89

Tualang honey improves memory performance and decreases depressive-like behavior in rats exposed to loud noise stress


1 Department of Physiology, School of Medical Sciences, Universiti Sains Malaysia, Malaysia
2 Institute of Health Sciences, Muscat, Oman

Correspondence Address:
Khairunnuur Fairuz Azman
Department of Physiology, School of Medical Sciences, Health Campus, Universiti Sains Malaysia, Kubang Kerian - 16150, Kota Bharu, Kelantan
Malaysia
Login to access the Email id

Source of Support: This project was supported by short-term grant of Universiti Sains Malaysia (304/PPSP/61313056) and grant from Ministry of Health of Oman (304/PPSP/6150117/M137)., Conflict of Interest: None


DOI: 10.4103/1463-1741.153388

Rights and Permissions

Recent evidence has exhibited dietary influence on the manifestation of different types of behavior induced by stressor tasks. The present study examined the effects of Tualang honey supplement administered with the goal of preventing or attenuating the occurrence of stress-related behaviors in male rats subjected to noise stress. Forty-eight adult male rats were randomly divided into the following four groups: i) nonstressed with vehicle, ii) nonstressed with Tualang honey, iii) stressed with vehicle, and iv) stressed with honey. The supplement was given once daily via oral gavage at 0.2 g/kg body weight. Two types of behavioral tests were performed, namely, the novel object recognition test to evaluate working memory and the forced swimming test to evaluate depressive-like behavior. Data were analyzed by a two-way analysis of variance (ANOVA) using IBM SPSS 18.0. It was observed that the rats subjected to noise stress expressed higher levels of depressive-like behavior and lower memory functions compared to the unexposed control rats. In addition, our results indicated that the supplementation regimen successfully counteracted the effects of noise stress. The forced swimming test indicated that climbing and swimming times were significantly increased and immobility times significantly decreased in honey-supplemented rats, thereby demonstrating an antidepressant-like effect. Furthermore, cognitive function was shown to be intensely affected by noise stress, but the effects were counteracted by the honey supplement. These findings suggest that subchronic exposure to noise stress induces depressive-like behavior and reduces cognitive functions, and that these effects can be attenuated by Tualang honey supplementation. This warrants further studies to examine the role of Tulang honey in mediating such effects.






[FULL TEXT] [PDF]*


        
Print this article     Email this article