Noise Health Close
 

Figure 8. Schematic diagram of phenotype of PMCA2 knockout and Ahl/Ahl. In this case both defective otocadherin forms weak bonds between stereocilia and low Ca+2 concentrations lead to extremely vulnerable stereocilia. In this case the “modifier of deaf waddler” is a common pathway based on the requirement for calcium.

Figure 8. Schematic diagram of phenotype of PMCA2 knockout and Ahl/Ahl. In this case both defective otocadherin forms weak bonds between stereocilia and low Ca+2 concentrations lead to extremely vulnerable
stereocilia. In this case the “modifier of deaf waddler” is a common pathway based on the requirement for calcium.