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| ARTICLE |
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| Year : 2013 | Volume
: 15
| Issue : 67 | Page : 388--397 |
Road traffic noise, air pollution components and cardiovascular events
Yvonne de Kluizenaar1, Frank J van Lenthe2, Antoon J.H. Visschedijk3, Peter Y.J. Zandveld4, Henk M.E. Miedema5, Johan P Mackenbach2
1 Urban Environment and Safety, The Netherlands Organization for Applied Scientific Research (TNO), P.O. Box 49, 2600 AA, Delft; Department of Public Health, Erasmus MC, University Medical Center Rotterdam, The Netherlands
2 Department of Public Health, Erasmus MC, University Medical Center Rotterdam, The Netherlands
3 Climate, Air and Sustainability, The Netherlands Organization for Applied Scientific Research (TNO), P.O. Box 80015, 3508 TA Utrecht, The Netherlands
4 Urban Environment and Safety, The Netherlands Organization for Applied Scientific Research (TNO), P.O. Box 80015, 3508 TA Utrecht, The Netherlands
5 Urban Environment and Safety, The Netherlands Organization for Applied Scientific Research (TNO), P.O. Box 49, 2600 AA, Delft, The Netherlands
Correspondence Address:
Yvonne de Kluizenaar
TNO, Postbus 49, 2600 AA, Delft
The Netherlands
 Source of Support: This work was funded by the Netherlands Ministry
of Housing, Spatial Planning and the Environment (VROM). The GLOBE
study is carried out by the Department of Public Health of the Erasmus
University Medical Centre in Rotterdam, in collaboration with Municipal
Public Health Service in the study region (GGD Brabant-Zuidoost). The
study has been and is supported by grants of the Ministry of Public Health,
Welfare and Sport, the Sick Fund Council, the Netherlands Organization
for Advancement of Research, Erasmus University, and the Health
Research and Development Council., Conflict of Interest: None  | Check |
DOI: 10.4103/1463-1741.121230
Traffic noise and air pollution have been associated with cardiovascular health effects. Until date, only a limited amount of prospective epidemiological studies is available on long-term effects of road traffic noise and combustion related air pollution. This study investigates the relationship between road traffic noise and air pollution and hospital admissions for ischemic heart disease (IHD: International Classification of Diseases (ICD9) 410-414) or cerebrovascular disease (cerebrovascular event [CVE]: ICD9 430-438). We linked baseline questionnaire data to 13 years of follow-up on hospital admissions and road traffic noise and air pollution exposure, for a large random sample (N = 18,213) of inhabitants of the Eindhoven region, Netherlands. Subjects with cardiovascular event during follow-up on average had higher road traffic noise day, evening, night level (L den) and air pollution exposure at the home. After adjustment for confounders (age, sex, body mass index, smoking, education, exercise, marital status, alcohol use, work situation, financial difficulties), increased exposure did not exert a significant increased risk of hospital admission for IHD or cerebrovascular disease. Relative risks (RRs) for a 5 th to 95 th percentile interval increase were 1.03 (0.88-1.20) for L den; 1.04 (0.90-1.21) for particulate matter (PM 10 ); 1.05 (0.91-1.20) for elemental carbon (EC); and 1.12 (096-1.32) for nitrogen dioxide (NO 2 ) in the full model. While the risk estimate seemed highest for NO 2 , for a 5 th to 95 th percentile interval increase, expressed as RRs per 1 μg/m 3 increases, hazard ratios seemed highest for EC (RR 1.04 [0.92-1.18]). In the subgroup of study participants with a history of cardiovascular disease, RR estimates seemed highest for noise exposure (1.19 [0.87-1.64] for L den); in the subgroup of elderly RR seemed highest for air pollution exposure (RR 1.24 [0.93-1.66] for NO 2 ).
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