Figure 10. (A) CAP input/output functions at 8 kHz from normal chinchillas and chinchillas treated with either a single dose (38 mg/kg, 20-30% IHC loss) or double dose (76 mg/kg, 80-90% IHC loss) of carboplatin. Change in amplitude roughly proportional to degree of IHC loss. (B) CAP visual detection threshold in single and double dose groups. Thresholds normal in single dose group, but significantly elevated in double dose group.