Figure 12. Transmission electron micrographs obtained 6-h postcarboplatin (left column) and 24-h post-carboplatin (right column). (A) Arrow shows swollen afferent terminal at base of IHC. (B) Large, swollen afferent terminal (arrow) distorts base of IHC. (C) Spiral ganglion neuron with small vacuoles (arrow) adjacent to plasma membrane. (D) Numerous large vacuoles in spiral ganglion neuron (arrow). (E) Proximal nerve fiber containing small vacuoles (arrows). (F) Numerous, large vacuoles in proximal nerve fiber.