Figure 2. (A) Average (n=5) cochleogram showing the percentage of missing OHCs and IHCs as a function of percent distance from the apex of the cochlea. Upper abscissa relates cochlear position to frequency (Greenwood, 1990). Chinchillas treated with 38 mg/kg of carboplatin. (B) Cochleogram from a chinchilla treated with a high dose (200 mg/kg) of carboplatin. Note OHC loss in base of cochlea and massive IHC loss throughout most of the cochlea.