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(A) Average cochleogram obtained from 4 guinea pigs exposed both to noise (OBN8kHz, Leq8h=85dB) and treated with gentamicin (40 mg/kg for 8 days). (B) Average cochleogram obtained from 4 control guinea pigs. Abscissa -upper trace length (mm) of the entire spiral course of the organ of Corti from the hook; lower trace: frequency map according to Greenwood (1990) . Ordinate : hair cell loss in percent. IHC: inner hair cell; OHC1: first row of outer hair cells; OHC2: second row; OHC3: third row. |
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