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Figure 3: Volcano plots of microarray data. Analysis of variance was used to identify differentially expressed candidates in each of the comparisons evaluated in this study. This analysis returned a P value for the observed difference (i.e., fold-change [FC]) in expression for a given probe. In the following plots, Log2 (FC) on the X-axis was plotted against Log10(P value) on the Y-axis. The red dots indicate probes that were ruled out for further analysis, while the green dots indicate probes that were ruled in for pathway analysis via Benjamini-Hochberg analyses using a false discovery rate (FDR) as indicated: (a) 116 dB SPL versus control-FDR = 0.15; (b) 110 dB SPL versus control-FDR = 0.15 |
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